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EXOG / ENDOGL1 is an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18.
Gene Name: | endo/exonuclease (5'-3'), endonuclease G-like |
Synonyms: | EXOG, Endonuclease G-like 1, Endonuclease G-like 2, ENGL, ENGL-b, ENGLA, ENGLB, ENDOGL1, ENGL-a, Nuclease EXOG, mitochondrial, Endo G-like 1, ENDOGL2 |
Target Sequences: | NM_005107 NP_005098.2 Q9Y2C4 |
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