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EXOC2 / SEC5

exocyst complex component 2

EXOC2 / SEC5 is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants.

Gene Name: exocyst complex component 2
Synonyms: EXOC2, Exocyst complex component 2, SEC5L1, Sec5p, Exocyst complex component Sec5, SEC5, SEC5-like 1, SEC5-like 1 (S. cerevisiae)
Target Sequences: NM_018303 NP_060773.3 Q96KP1

☰ Filters
Antibodies (12)
Proteins (2)
Over-Expression Lysate (2)
Primary (12)
EXOC2 / SEC5 (14)
Human (12)
Mouse (4)
Rat (4)
Chimpanzee (3)
Gibbon (3)
IHC (5)
IHC-P (2)
WB (10)
ELISA (4)
IF (1)
IP (2)
Peptide-ELISA (1)
rabbit (11)
mouse (1)
Product Group
IHCPlus (1)
IgG (5)
IgG1 (1)
monoclonal mc (1)
polyclonal pc (11)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (9)
N-Terminus (3)
aa1-17 (1)
aa1-220 (1)
aa406-455 (1)
No (14)
Myc-DDK (Flag) (2)
Human (1)
293T Cells (1)
HEK 293 Cells (1)
EXOC2 / SEC5 Antibody - Anti-EXOC2 / SEC5 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 40 ug/ml.
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EXOC2 / SEC5 Rabbit anti-Human Polyclonal (aa1-17) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
EXOC2 / SEC5 Antibody - 1:100 staining human brain carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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EXOC2 / SEC5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
EXOC2 / SEC5 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$371
Select
EXOC2 / SEC5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
EXOC2 / SEC5 Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.
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EXOC2 / SEC5 Rabbit anti-Human Polyclonal (aa1-220) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
Select
EXOC2 / SEC5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
EXOC2 / SEC5 Antibody - EXOC2 / SEC5 antibody Western Blot of 721_B. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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EXOC2 / SEC5 Rabbit anti-Human Polyclonal (aa406-455) Antibody
Human
WB
Unconjugated
100 µl/$424
EXOC2 / SEC5 Antibody - EXOC2 / SEC5 antibody Western Blot of 721_B. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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EXOC2 / SEC5 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Human, Chimpanzee, Gibbon
WB
HRP Conjugated
100 µl/$469
EXOC2 / SEC5 Antibody - EXOC2 / SEC5 antibody Western Blot of 721_B. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
EXOC2 / SEC5 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Human, Chimpanzee, Gibbon
WB
Biotin Conjugated
100 µl/$469
EXOC2 / SEC5 Antibody - EXOC2 / SEC5 antibody Western Blot of 721_B. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
EXOC2 / SEC5 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Human, Chimpanzee, Gibbon
WB
FITC Conjugated
100 µl/$469
EXOC2 / SEC5 Antibody - Western blot analysis of Sec5 expression in MCF7 (A); HeLa (B); mouse lung (C); rat brain (D) whole cell lysates.
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EXOC2 / SEC5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
EXOC2 / SEC5 Antibody - Western blot analysis of extract of various cells.
Select
EXOC2 / SEC5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
EXOC2 / SEC5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
103.9 kDa
100 µg/$494
EXOC2 / SEC5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
103.9 kDa
20 µg/$150
Viewing 1-14 of 14 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).