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ESRRB / ERR Beta

estrogen-related receptor beta

Estrogen-related receptor beta (ERR beta) a NR3 Steroid Receptor, has been shown to affect early placental development. ERR beta also can act as a repressor of transcriptional activity mediated by the glucocorticoid receptor (GR). ERR beta binds as a monomer to the extended half-site TNAAGTGCA and as a homodimer to the estrogen response element (ERE), palindromic thyroid hormone response element (TRE(pal)), and SF-1 response element, but not to the glucocorticoid response element (GRE). ERR beta mutations lead to abnormal development of the chorion and defective diploid trophoblast proliferation, and are lethal during midgestation.

Gene Name: estrogen-related receptor beta
Family/Subfamily: NHR , NR3 Steroid receptor
Synonyms: ESRRB, DFNB35, ERRb, ERRbeta-2, ESRL2, Estrogen receptor-like 2, ERR-beta, ERRB2, ERRbeta, NR3B2, Nuclear receptor ERRB2, Orphan nuclear receptor, ERR beta-2, ERR2, Estrogen-related receptor 2, Estrogen-related receptor beta, Steroid hormone receptor ERR2
Target Sequences: NM_004452 NP_004443.3 O95718

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Proteins (7)
Over-Expression Lysate (4)
Recombinant (3)
ESRRB / ERR Beta (7)
No (7)
GST, N-terminus (1)
Myc-DDK (Flag) (5)
Human (4)
Mouse (1)
293T Cells (2)
E. coli (1)
HEK 293 Cells (3)
Wheat Germ Extract (1)
ESRRB / ERR Beta Protein - 12.5% SDS-PAGE Stained with Coomassie Blue
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Wheat Germ Extract
GST, N-terminus
81.4 kDa
2 µg/$439
ESRRB / ERR Beta Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
56 kDa
100 µg/$494
ESRRB / ERR Beta Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
56 kDa
20 µg/$215
ESRRB / ERR Beta Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
56 kDa
20 µg/$150
ESRRB / ERR Beta Protein - Purified recombinant protein ESRRB was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
56 kDa
20 µg/$1,107
ESRRB / ERR Beta Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
56 kDa
100 µg/$710
ESRRB / ERR Beta Protein - Recombinant Estrogen Related Receptor Beta (ERRb) by SDS-PAGE
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E. coli
None
35.1kDa
10 µg/$283; 50 µg/$452; 200 µg/$902; 100 µg/$722; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).