ESR2 / ER Beta

estrogen receptor 2 (ER beta)

Estrogen receptor beta (ER beta), a NR3 Steroid Receptor, has been shown to have physiological functions in the central nervous system, cardiovascular system, immune system, urogenital tract, gastrointestinal tract, and in bone, kidney, and lung. Mice lacking the gene for ER beta show defective ovary development, reduced fertility, abnormal bladder and prostate development, and impaired vascular system functions that lead to hypertension in aging. ER beta is phosphorylated upon ligand activation and binds to target DNA as a homodimer. At least eight alternatively spliced isoforms of ER beta have been documented, many of which show tissue-specific expression patterns. A novel and functionally distinct isoform of human ER beta (ER beta548), which includes an extended amino-terminal domain has been identified recently by Wilkinson et al. 2002. ER beta has been suggested to affect carcinogenesis in smooth muscle, urogenital tract, breast, and colonic tissues.

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Products

Proteins (14)

Type

Over-Expression Lysate (5)

Recombinant (9)

Target

ESR2 / ER Beta (14)

Publications

No (14)

Tag

6His, N-terminus (2)

6His-SUMO, N-terminus (1)

DDK,C-terminus (1)

GST (1)

GST, N-terminus (1)

His (3)

Myc-DDK (Flag) (5)

Species

Human (11)

Mouse (1)

Source

293T Cells (3)

E. coli (6)

HEK 293 Cells (2)

Sf9 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (2)

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Human ESR2 / ER Beta Protein (Recombinant His) (Full Length) - LS-G20713

Source:

E. coli

Tag:

His

Molecular Weight:

63.1 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Mouse ESR2 / ER Beta Protein (Recombinant His) (aa46-530) - LS-G12189

Source:

E. coli

Tag:

His

Molecular Weight:

55.6 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Human ESR2 / ER Beta Protein (Recombinant DDK,C-terminus) - LS-G142335

Source:

Sf9 Cells

Tag:

DDK,C-terminus

Molecular Weight:

59 kDa

Price:

20 µg/$677

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ESR2 / ER Beta Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G120301

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

55.3 kDa

Price:

100 µg/$710

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Human ESR2 / ER Beta Protein (Recombinant 6His, N-terminus) (Met1-Ala323) - LS-G139574

Source:

E. coli

Tag:

6His, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

38.1 kDa

Price:

10 µg/$288; 50 µg/$436

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Human ESR2 / ER Beta Protein (Recombinant GST) (Full Length) - LS-G28391

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

61.27 kDa

Price:

2 µg/$439

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Human ESR2 / ER Beta Protein (Recombinant GST, N-terminus) (aa22-121) - LS-G58491

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human ESR2 / ER Beta Protein (Recombinant 6His-SUMO, N-terminus) (aa2-323) - LS-G56242

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human ESR2 / ER Beta Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79819

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

55.3 kDa

Price:

20 µg/$215

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Human ESR2 / ER Beta Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79821

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

55.3 kDa

Price:

20 µg/$150

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Human ESR2 / ER Beta Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79823

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

59 kDa

Price:

20 µg/$215

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ESR2 / ER Beta Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99439

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

59 kDa

Price:

100 µg/$710

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Human ESR2 / ER Beta Protein (Recombinant 6His, N-terminus) (Met1-Ala323) - LS-G39667

Source:

E. coli

Tag:

6His, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

38.1kD

Price:

10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157

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Human ESR2 / ER Beta Protein (Recombinant His) (aa149-213) - LS-G12188

Source:

E. coli

Tag:

His

Molecular Weight:

10.0 kDa

Price:

10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723

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