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ERP44

endoplasmic reticulum protein 44

TXNDC4/ERp44/KIAA0573 was identified via its interaction with Erol-Lalpha, which in turn has been shown to regulate oxidative protein folding by selectively oxidizing protein disulfide isomerase. TXNDC4 is induced during ER stress and forms mixed disulfides with both hEROs and cargo folding intermediates. Over expression has been shown to alter the equilibrium of the different Ero1-Lalpha redox isoforms suggesting that TXNDC4 may be involved in the control of oxidative protein folding. It has also been suggested that TXNDC4 senses the environment in the ER lumen because it modulates IP3R1 (1,4,5-triphosphate receptor type 1) activity thereby regulating cytosolic calcium concentrations and intraluminal conditions.

Gene Name: endoplasmic reticulum protein 44
Synonyms: ERP44, ER protein 44, PDIA10, TXNDC4, KIAA0573
Target Sequences: AB011145 BAA25499.1 Q9BS26

☰ Filters
Products
Proteins (10)
Over-Expression Lysate (2)
Recombinant (8)
ERP44 (10)
No (10)
6His, C-terminus (2)
GST (2)
His (1)
His-SUMO (1)
His-T7, N-terminus (1)
Myc-DDK (Flag) (3)
Human (8)
Mouse (1)
293T Cells (1)
E. coli (3)
HEK 293 Cells (2)
Human Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (1)
Purified (3)
Low endotoxin level (2)
ERP44 Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
ERP44 Protein - Purified recombinant protein ERP44 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
46.8 kDa
20 µg/$1,107
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
44.2kD
10 µg/$281; 50 µg/$420; 500 µg/$1,585; 1 mg/$2,157
ERP44 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
46.8 kDa
100 µg/$494
ERP44 Protein
Select
E. coli
His-SUMO
59.7 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
ERP44 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
46.8 kDa
20 µg/$150
ERP44 Protein
Select
GST
36.63kDa
10 µg/$479; 25 µg/$670
ERP44 Protein - Recombinant Endoplasmic Reticulum Protein 44 (ERP44) by SDS-PAGE
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E. coli
His-T7, N-terminus
40.9kDa
10 µg/$265; 50 µg/$347; 200 µg/$682; 100 µg/$545; 1 mg/$1,690; 500 µg/$1,270; 5 mg/$2,637; 2 mg/$1,866
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
44.2 kDa
10 µg/$368; 50 µg/$504
ERP44 Protein - 12.5% SDS-PAGE of human TXNDC4 stained with Coomassie Blue
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Wheat Germ Extract
GST
67.21 kDa
10 µg/$479; 25 µg/$670
Viewing 1-10 of 10 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).