ERP44

endoplasmic reticulum protein 44

TXNDC4/ERp44/KIAA0573 was identified via its interaction with Erol-Lalpha, which in turn has been shown to regulate oxidative protein folding by selectively oxidizing protein disulfide isomerase. TXNDC4 is induced during ER stress and forms mixed disulfides with both hEROs and cargo folding intermediates. Over expression has been shown to alter the equilibrium of the different Ero1-Lalpha redox isoforms suggesting that TXNDC4 may be involved in the control of oxidative protein folding. It has also been suggested that TXNDC4 senses the environment in the ER lumen because it modulates IP3R1 (1,4,5-triphosphate receptor type 1) activity thereby regulating cytosolic calcium concentrations and intraluminal conditions.

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Products

Proteins (10)

Type

Over-Expression Lysate (2)

Recombinant (8)

Target

ERP44 (10)

Publications

No (10)

Tag

6His, C-terminus (2)

GST (2)

His (1)

His-SUMO (1)

His-T7, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (8)

Mouse (1)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

Human Cells (1)

Mammalian Cells (1)

Wheat Germ Extract (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (2)

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Human ERP44 Protein (Recombinant His) - LS-G906

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human ERP44 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67481

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.8 kDa

Price:

20 µg/$1,107

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Human ERP44 Protein (Recombinant 6His, C-terminus) (Glu30-Asp402) - LS-G39486

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

44.2kD

Price:

10 µg/$281; 50 µg/$420; 500 µg/$1,585; 1 mg/$2,157

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ERP44 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101287

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.8 kDa

Price:

100 µg/$494

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Human ERP44 Protein (Recombinant His-SUMO) (aa30-406) - LS-G21907

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

59.7 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human ERP44 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79954

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.8 kDa

Price:

20 µg/$150

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Human ERP44 Protein (Recombinant GST) - LS-G132151

Tag:

GST

Molecular Weight:

36.63kDa

Price:

10 µg/$479; 25 µg/$670

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Mouse ERP44 Protein (Recombinant His-T7, N-terminus) (Met1-Ala322) - LS-G133473

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

40.9kDa

Price:

10 µg/$265; 50 µg/$347; 200 µg/$682; 100 µg/$545; 1 mg/$1,690; 500 µg/$1,270; 5 mg/$2,637; 2 mg/$1,866

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Human ERP44 Protein (Recombinant 6His, C-terminus) (Glu30-Asp402) - LS-G139449

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

44.2 kDa

Price:

10 µg/$368; 50 µg/$504

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Human ERP44 Protein (Recombinant GST) (Full Length) - LS-G32722

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

67.21 kDa

Price:

10 µg/$479; 25 µg/$670

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