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ERP29 is a reticuloplasmin, a protein which resides in the lumen of the endoplasmic reticulum (ER). The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Name: | endoplasmic reticulum protein 29 |
Synonyms: | ERP29, C12orf8, ERp28, ERp31, PDI-DB, PDIA9 |
Target Sequences: | NM_006817 NP_006808.1 P30040 |
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