ERO1LB

ERO1-like beta (S. cerevisiae)

Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Other protein disulfide isomerase family members can also be reoxidized, but at lower rates compared to P4HB, including PDIA2 (50% of P4HB reoxidation rate), as well as PDIA3, PDIA4, PDIA6 and NXNDC12 (<10%). Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. May be involved in oxidative proinsulin folding in pancreatic cells, hence may play a role in glucose homeostasis.

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ELISA Kits (2)

Type

Custom (1)

Sandwich (1)

Target

ERO1LB (2)

Reactivity

Human (1)

Mouse (1)

Format

96-Well Strip Plate (2)

Publications

No (2)

Sample Type

Plasma (1)

Serum (1)

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Mouse ERO1LB (Custom) ELISA Kit - LS-F66032

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Price:

1 Plate/$669

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Human ERO1LB (Sandwich ELISA) ELISA Kit - LS-F66587

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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