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ERO1LB

ERO1-like beta (S. cerevisiae)

Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Other protein disulfide isomerase family members can also be reoxidized, but at lower rates compared to P4HB, including PDIA2 (50% of P4HB reoxidation rate), as well as PDIA3, PDIA4, PDIA6 and NXNDC12 (<10%). Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. May be involved in oxidative proinsulin folding in pancreatic cells, hence may play a role in glucose homeostasis.

Gene Name: ERO1-like beta (S. cerevisiae)
Synonyms: ERO1LB, ERO1-L(beta), ERO1-like protein beta, ERO1-like beta (S. cerevisiae), ERO1-L-beta, Oxidoreductin-1-L-beta
Target Sequences: NM_019891

Publications (2)

1
Proteomic analysis of solid pseudopapillary tumor of the pancreas reveals dysfunction of the endoplasmic reticulum protein processing pathway. Zhu Y, Xu H, Chen H, Xie J, Shi M, Shen B, Deng X, Liu C, Zhan X, Peng C. Molecular & cellular proteomics : MCP. 2014 13:2593-603. (WB; Human, Rat) [Full Text Article] [PubMed:24997997] [PMC:PMC4188989]
2
The Immunohistochemical Evaluation of Solid Pseudopapillary Tumors of the Pancreas and Pancreatic Neuroendocrine Tumors Reveals ERO1Lß as a New Biomarker. Xie J, Zhu Y, Chen H, Shi M, Gu J, Zhang J, Shen B, Deng X, Zhan X, Peng C. Medicine. 2016 95:e2509. (WB; Human) [Full Text Article] [PubMed:26765469] [PMC:PMC4718295]

☰ Filters
Antibodies (15)
Proteins (4)
ELISA Kits (2)
Custom (1)
Over-Expression Lysate (2)
Primary (15)
Recombinant (2)
Sandwich (1)
ERO1LB (21)
Human (16)
Mouse (14)
Rat (1)
IHC (11)
IHC-P (3)
WB (12)
Flo (7)
ELISA (12)
IF (1)
Peptide-ELISA (1)
rabbit (15)
Product Group
IHCPlus (2)
IgG (14)
polyclonal pc (15)
96-Well Strip Plate (2)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (7)
aa266-293 (7)
No (21)
Plasma (1)
Serum (1)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
ERO1LB Antibody - Anti-ERO1LB antibody IHC staining of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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ERO1LB Rabbit anti-Human Polyclonal (aa266-293) Antibody
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
200 µl/$460
ERO1LB Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
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ERO1LB Rabbit anti-Human Polyclonal (aa266-293) Antibody
Mouse, Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
50 µl/$485
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ERO1LB Rabbit anti-Human Polyclonal (aa266-293) (Biotin) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
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ERO1LB Rabbit anti-Human Polyclonal (aa266-293) (FITC) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
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ERO1LB Rabbit anti-Human Polyclonal (aa266-293) (APC) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
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ERO1LB Rabbit anti-Human Polyclonal (aa266-293) (PE) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
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ERO1LB Rabbit anti-Human Polyclonal (aa266-293) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
ERO1LB Antibody - Immunohistochemistry of paraffin-embedded human pancreatic tissue using antibody at dilution of 1:100.
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ERO1LB Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
ERO1LB Rabbit anti-Human Polyclonal (HRP) Antibody
Mouse, Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
ERO1LB Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
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ERO1LB Rabbit anti-Human Polyclonal (FITC) Antibody
Mouse, Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
ERO1LB Antibody - 1:100 staining human liver carcinoma tissues by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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ERO1LB Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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ERO1LB Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
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ERO1LB Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
ERO1LB Antibody - Western blot analysis of extracts of Mouse brain cells.
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ERO1LB Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
ERO1LB Protein - 12.5% SDS-PAGE of human ERO1LB stained with Coomassie Blue
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Wheat Germ Extract
GST
79.9 kDa
10 µg/$479; 25 µg/$670
ERO1LB Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
53.4 kDa
20 µg/$150
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HEK 293 Cells
Myc-DDK (Flag)
53.4 kDa
20 µg/$1,107
ERO1LB ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
1 Plate/$783
ERO1LB ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
ERO1LB Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
53.4 kDa
100 µg/$494
Viewing 1-21 of 21 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).