ERCC6 / CSB

excision repair cross-complementing rodent repair deficiency, complementation group 6

Essential factor involved in transcription-coupled nucleotide excision repair which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation. It recruits the CSA complex (DCX(ERCC8) complex), nucleotide excision repair proteins and EP300 to the at sites of RNA polymerase II-blocking lesions.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

ERCC6 / CSB (5)

Publications

No (5)

Tag

GST, N-terminus (1)

His, N-Terminal (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

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ERCC6 / CSB Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123384

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

168.2 kDa

Price:

100 µg/$710

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Human ERCC6 / CSB Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75855

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

168.2 kDa

Price:

20 µg/$215

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Human ERCC6 / CSB Protein (Recombinant GST, N-terminus) (aa1394-1493) - LS-G58484

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human ERCC6 / CSB Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65593

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

168.2 kDa

Price:

20 µg/$1,107

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Human ERCC6 / CSB Protein (Recombinant His, N-Terminal) (Val843-Tyr1002) - LS-G133114

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

22.6kDa

Price:

10 µg/$267; 50 µg/$352; 200 µg/$702; 100 µg/$562; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900

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