EPHB2 / EPH Receptor B2

EPH receptor B2

Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Functions in axon guidance during development. Involved in the guidance of commissural axons, that form a major interhemispheric connection between the 2 temporal lobes of the cerebral cortex. Also involved in guidance of contralateral inner ear efferent growth cones at the midline and of retinal ganglion cell axons to the optic disk. In addition to axon guidance, also regulates dendritic spines development and maturation and stimulates the formation of excitatory synapses. Upon activation by EFNB1, abolishes the ARHGEF15-mediated negative regulation on excitatory synapse formation. Controls other aspects of development including angiogenesis, palate development and in inner ear development through regulation of endolymph production. Forward and reverse signaling through the EFNB2/EPHB2 complex regulate movement and adhesion of cells that tubularize the urethra and septate the cloaca. May function as a tumor suppressor.

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ELISA Kits (4)

Type

Cell-Based (1)

Custom (1)

Sandwich (2)

Target

EPHB2 / EPH Receptor B2 (4)

Reactivity

Human (4)

Format

96-Well Microplate (2)

96-Well Strip Plate (2)

Publications

No (4)

Sample Type

Adherent Cell Cultures (1)

Plasma (2)

Serum (2)

Tissue Homogenates (2)

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Human EPHB2 / EPH Receptor B2 (Cell-Based ELISA) ELISA Kit - LS-F1969

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$618

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Human EPHB2 / EPH Receptor B2 (Sandwich ELISA) ELISA Kit - LS-F51845

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$958

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Human EPHB2 / EPH Receptor B2 (Sandwich ELISA) ELISA Kit - LS-F36879

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human EPHB2 / EPH Receptor B2 (Custom ELISA) ELISA Kit - LS-F50368

Type:

Custom

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$923

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