EPHA2 / EPH Receptor A2

EPH receptor A2

Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway. May also participate in UV radiation-induced apoptosis and have a ligand-independent stimulatory effect on chemotactic cell migration. During development, may function in distinctive aspects of pattern formation and subsequently in development of several fetal tissues. Involved for instance in angiogenesis, in early hindbrain development and epithelial proliferation and branching morphogenesis during mammary gland development. Engaged by the ligand ephrin-A5/EFNA5 may regulate lens fiber cells shape and interactions and be important for lens transparency development and maintenance. With ephrin-A2/EFNA2 may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis.

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Products

ELISA Kits (10)

Type

Sandwich (9)

Sandwich CLIA (1)

Target

EPHA2 / EPH Receptor A2 (10)

Reactivity

Human (6)

Guinea pig (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (2)

96-Well Strip Plate (6)

Publications

No (10)

Sample Type

Cell Culture Supernatants (2)

Cell Lysates (1)

EDTA Plasma (1)

Heparin Plasma (1)

Plasma (5)

Serum (6)

Tissue Homogenates (2)

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Human EPHA2 / EPH Receptor A2 (CLIA) ELISA Kit - LS-F29608

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

15.625 - 1000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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Human EPHA2 / EPH Receptor A2 (Sandwich ELISA) ELISA Kit - LS-F23977

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Human EPHA2 / EPH Receptor A2 (Sandwich ELISA) ELISA Kit - LS-F35520

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human EPHA2 / EPH Receptor A2 (Sandwich ELISA) ELISA Kit - LS-F57308

Type:

Sandwich

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Sample Types:

Cell Culture Supernatants, EDTA Plasma, Heparin Plasma, Serum

Price:

1 Plate/$795

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Guinea pig EPHA2 / EPH Receptor A2 (Sandwich ELISA) ELISA Kit - LS-F48906

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

3.906 - 250 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Monkey EPHA2 / EPH Receptor A2 (Sandwich ELISA) ELISA Kit - LS-F48907

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Porcine EPHA2 / EPH Receptor A2 (Sandwich ELISA) ELISA Kit - LS-F48908

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Rabbit EPHA2 / EPH Receptor A2 (Sandwich ELISA) ELISA Kit - LS-F48909

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

3.125 - 200 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Human EPHA2 / EPH Receptor A2 (Sandwich ELISA) ELISA Kit - LS-F51841

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$958

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Human EPHA2 / EPH Receptor A2 (Sandwich ELISA) ELISA Kit - LS-F49916

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.082 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$700

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