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Canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. Ectonucleoside NTPDases catalyze the hydrolysis of gamma- and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides. Has activity toward ATP, ADP, UTP and UDP, but not toward AMP.
Gene Name: | ectonucleoside triphosphate diphosphohydrolase 8 |
Synonyms: | ENTPD8, NTPDase 8, NTPDase-8, NTPDase8, UNQ2492, E-NTPDase 8, Ecto-ATP-diphosphohydrolase, GLSR2492 |
Target Sequences: | Q5MY95 Q5MY95 |
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