Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
ENTPD6/CD39L2 exists a both a membrane form and as a secreted protein. ENTPD6, a nucleoside triphosphate diphosphohydrolase, preferentially hydrolyzes nucleoside diphosphates and is strongly activated in the presence of divalent cations. Circulating levels of nucleotides in the blood regulate a variety of physiological states including cardiac function, hormone secretion, immune responses, neurotransmission, and platelet aggregation. Expression of ENTPD6/CD39L2 is found predominantly in human heart myocytes and capillary endothelial cells and may be a mediator of platelet aggregation in the heart.