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Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors.
Gene Name: | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) |
Family/Subfamily: | Phosphodiesterase - Other , not assigned-Phosphodiesterase - Other |
Synonyms: | ENPP4, E-NPP 4, KIAA0879, NPP-4, NPP4 |
Target Sequences: | BC018054 AAH18054.1 Q9Y6X5 |
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