ENPP2 / Autotaxin

ectonucleotide pyrophosphatase/phosphodiesterase 2

Hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor.

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Products

Proteins (8)

Type

Over-Expression Lysate (2)

Recombinant (6)

Target

ENPP2 / Autotaxin (8)

Publications

No (8)

Tag

His (2)

His,C-terminus (1)

His,N-terminus (1)

His-T7 (2)

Myc-DDK (Flag) (2)

Species

Human (4)

Mouse (2)

Rat (1)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

Human Cells (1)

Mammalian Cells (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (4)

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Rat ENPP2 / Autotaxin Protein (Recombinant His-T7) (aa54-254) - LS-G24782

Source:

E. coli

Tag:

His-T7

Molecular Weight:

26.5 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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Mouse ENPP2 / Autotaxin Protein (Recombinant His) (aa597-862) - LS-G140853

Source:

E. coli

Sequence Length:

265 AA

Tag:

His

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

29.26 kDa

Price:

10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531

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Human ENPP2 / Autotaxin Protein (Recombinant His,N-terminus) (Asp49-Ile863) - LS-G138425

Source:

HEK 293 Cells

Tag:

His,N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

96 kDa

Price:

50 µg/$567; 500 µg/$2,999

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Mouse ENPP2 / Autotaxin Protein (Recombinant His) (Ser49-Ile862) - LS-G98131

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

96 kDa

Price:

50 µg/$567; 500 µg/$2,999

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ENPP2 / Autotaxin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G120236

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

99 kDa

Price:

100 µg/$494

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Human ENPP2 / Autotaxin Protein (Recombinant His-T7) (aa637-905) - LS-G14884

Source:

E. coli

Tag:

His-T7

Molecular Weight:

35.0 kDa

Price:

10 µg/$294; 50 µg/$522; 100 µg/$832; 200 µg/$1,034; 1 mg/$2,192; 500 µg/$1,712; 5 mg/$3,641; 2 mg/$2,383

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Human ENPP2 / Autotaxin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74678

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

99 kDa

Price:

20 µg/$150

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Human ENPP2 / Autotaxin Protein (Recombinant His,C-terminus) (Ala36-Ile863) - LS-G139822

Source:

Mammalian Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

90 kDa

Price:

10 µg/$288; 50 µg/$436

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