Endothelin 3 / EDN3

endothelin 3

Endothelin 3 / EDN3 is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Products

Proteins (7)

Type

Over-Expression Lysate (4)

Recombinant (3)

Target

Endothelin 3 / EDN3 (7)

Publications

No (7)

Tag

GST (1)

His (1)

His-T7 (1)

Myc-DDK (Flag) (4)

Species

Human (4)

Rat (1)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (2)

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Rat Endothelin 3 / EDN3 Protein (Recombinant His-T7) (aa20-167) - LS-G24876

Source:

E. coli

Tag:

His-T7

Molecular Weight:

20.2 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Human Endothelin 3 / EDN3 Protein (Recombinant GST) (Full Length) - LS-G28294

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

51.92 kDa

Price:

10 µg/$479; 25 µg/$670

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Human Endothelin 3 / EDN3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81207

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

22.8 kDa

Price:

20 µg/$150

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Human Endothelin 3 / EDN3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81206

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

25.45 kDa

Price:

20 µg/$150

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Endothelin 3 / EDN3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102921

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

22.8 kDa

Price:

100 µg/$494

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Endothelin 3 / EDN3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G98922

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

25.45 kDa

Price:

100 µg/$494

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Human Endothelin 3 / EDN3 Protein (Recombinant His) - LS-G3167

Source:

E. coli

Tag:

His

Price:

10 µg/$361; 50 µg/$739

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