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Condensing enzyme that elongates saturated and monounsaturated very long chain fatty acids (VLCFAs). Elongates C24:0 and C26:0 acyl-CoAs. Seems to represent a photoreceptor-specific component of the fatty acid elongation system residing on the endoplasmic reticulum. May be implicated in docosahexaenoic acid (DHA) biosynthesis, which requires dietary consumption of the essential alpha-linolenic acid and a subsequent series of three elongation steps. May play a critical role in early brain and skin development.
Gene Name: | ELOVL fatty acid elongase 4 |
Synonyms: | ELOVL4, Cancer/testis antigen 118, CT118, ELOVL FA elongase 4, ADMD, ISQMR, STGD2, STGD3, ELOVL fatty acid elongase 4 |
Target Sequences: | NM_022726 NP_073563.1 Q9GZR5 |
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