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EIF6

eukaryotic translation initiation factor 6

Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene.

Gene Name: eukaryotic translation initiation factor 6
Synonyms: EIF6, B(2)GCN homolog, B4 integrin interactor, CAB, EIF-6, p27(BBP), p27BBP, B(2)gcn, ITGB4BP
Target Sequences: NM_002212 NP_002203.1 P56537

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Products
Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
EIF6 (5)
No (5)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
EIF6 Protein - 12.5% SDS-PAGE of human EIF6 stained with Coomassie Blue
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Wheat Germ Extract
GST
53 kDa
10 µg/$479; 25 µg/$670
EIF6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
26.4 kDa
100 µg/$494
EIF6 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
EIF6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
26.4 kDa
20 µg/$150
EIF6 Protein - Purified recombinant protein EIF6 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
26.4 kDa
20 µg/$1,107
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).