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EIF4G1 / EIF4G

eukaryotic translation initiation factor 4 gamma, 1

EIF4G1 / EIF4G is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.

Gene Name: eukaryotic translation initiation factor 4 gamma, 1
Synonyms: EIF4G1, EIF4-gamma, EIF-4-gamma 1, EIF-4G1, EIF4F, EIF4G, p220, PARK18, EIF-4G 1, EIF4GI
Target Sequences: NM_004953 NP_004944.3 Q04637

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Products
Proteins (11)
Over-Expression Lysate (4)
Recombinant (7)
EIF4G1 / EIF4G (11)
No (11)
10His-B2M-JD, N-terminus + Myc, C-terminus (1)
GST (2)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (6)
Human (9)
293T Cells (2)
E. coli (2)
HEK 293 Cells (4)
Wheat Germ Extract (2)
Yeast (1)
Purified (2)
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E. coli
GST
67 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
EIF4G1 / EIF4G Protein
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Yeast
His
41.6 kD
100 µg/$446; 20 µg/$336; 1 mg/$1,460
EIF4G1 / EIF4G Protein - 12.5% SDS-PAGE of human EIF4G1 stained with Coomassie Blue
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Wheat Germ Extract
GST
96.58 kDa
2 µg/$439
EIF4G1 / EIF4G Protein - Purified recombinant protein EIF4G1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
154.6 kDa
20 µg/$1,107
EIF4G1 / EIF4G Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
10His-B2M-JD, N-terminus + Myc, C-terminus
46.6 kDa
1 mg/$1,355; 100 µg/$420; 20 µg/$323
EIF4G1 / EIF4G Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
154.6 kDa
100 µg/$710
EIF4G1 / EIF4G Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
175.3 kDa
100 µg/$710
EIF4G1 / EIF4G Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
154.6 kDa
20 µg/$215
EIF4G1 / EIF4G Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
175.3 kDa
20 µg/$215
EIF4G1 / EIF4G Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
EIF4G1 / EIF4G Protein - Purified recombinant protein EIF4G1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
175.3 kDa
20 µg/$1,107
Viewing 1-11 of 11 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).