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EIF2B5 is one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.
Gene Name: | eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa |
Synonyms: | EIF2B5, CACH, EIF2BE, EIF-2B, LVWM, CLE, EIF2Bepsilon |
Target Sequences: | U23028 AAC50646.1 Q13144 |
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