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EGR2

early growth response 2

EGR2 is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene.

Gene Name: early growth response 2
Family/Subfamily: Transcription factor , not assigned-Transcription factor
Synonyms: EGR2, CMT1D, CMT4E, Early growth response 2, E3 SUMO-protein ligase EGR2, EGR-2, KROX20, Krox-20, AT591, Zinc finger protein Krox-20
Target Sequences: NM_000399 NP_000390.2 P11161

Publications (2)

1
Contribution of Schwann Cells to Remyelination in a Naturally Occurring Canine Model of CNS Neuroinflammation. Kegler K, Spitzbarth I, Imbschweiler I, Wewetzer K, Baumgärtner W, Seehusen F. PloS one. 2015 10:e0133916. (IHC, IF; Canine) [Full Text Article] [PubMed:26196511] [PMC:PMC4510361] Related Antibodies: LS-B3577.
2
Neural crest stem cells protect spinal cord neurons from excitotoxic damage and inhibit glial activation by secretion of brain-derived neurotrophic factor. Nikos Schizas, N König, B Andersson, S Vasylovska, J Hoeber, E N Kozlova, N P Hailer. Cell and tissue research. 2018 Jun;372:493-505. [Full Text Article] [PubMed:29516218] [PMC:PMC5949140] Related Antibodies: LS-B3577.

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Proteins (12)
Over-Expression Lysate (8)
Recombinant (4)
EGR2 (12)
No (12)
GST (1)
GST, N-terminus (1)
His (1)
His-T7 (1)
Myc-DDK (Flag) (8)
Human (7)
Mouse (1)
293T Cells (4)
E. coli (2)
HEK 293 Cells (4)
Wheat Germ Extract (2)
Purified (1)
EGR2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
50.1 kDa
100 µg/$710
EGR2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
50.1 kDa
100 µg/$494
EGR2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
50.1 kDa
100 µg/$494
EGR2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
44.8 kDa
100 µg/$494
EGR2 Protein - Recombinant  Early Growth Response Protein 2 By SDS-PAGE
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E. coli
His-T7
31.4 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
EGR2 Protein - 12.5% SDS-PAGE of human EGR2 stained with Coomassie Blue
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Wheat Germ Extract
GST
76.7 kDa
2 µg/$439
EGR2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
50.1 kDa
20 µg/$215
EGR2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
44.8 kDa
20 µg/$150
EGR2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
50.1 kDa
20 µg/$150
EGR2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
50.1 kDa
20 µg/$150
EGR2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
EGR2 Protein - Recombinant Early Growth Response Protein 2 By SDS-PAGE
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E. coli
His
29.5 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
Viewing 1-12 of 12 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).