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EGFL7
EGF-like-domain, multiple 7
Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cell adhesion to the extracellular matrix and angiogenesis.
| Gene Name: | EGF-like-domain, multiple 7 |
| Synonyms: | EGFL7, EGF-like-domain, multiple 7, RP11-251M1.2, VE-STATIN, NOTCH4-like protein, ZNEU1, EGF-like protein 7, MEGF7, Vascular endothelial statin |
| Target Sequences: | NM_016215 NP_057299.1 Q9UHF1 |
Publications (2)
1
EGFL7 Antagonizes NOTCH Signaling and Represents a Novel Therapeutic Target in Acute Myeloid Leukemia. Marius Bill, Aparna Pathmanathan, Malith Karunasiri, Changxian Shen, Matthew H Burke, Parvathi Ranganathan, Dimitrios Papaioannou, Nina C Zitzer, Katiri Snyder, Allison LaRocco, Allison E Walker, Zachary J Brannan, Ansel P Nalin, Aharon G Freud, Mikhail M Dikov, Xiaoli Zhang, Clara D Bloomfield, Ramiro Garzon, Adrienne M Dorrance. Clinical cancer research : an official journal of the American Association for Cancer Research. 2020 February;26:669-678. [Full Text Article]
[PubMed:31672772]
Related Antibodies: LS-C153302, LS-C40134.
2
Prognostic and biological significance of the proangiogenic factor EGFL7 in acute myeloid leukemia. Dimitrios Papaioannou, Changxian Shen, Deedra Nicolet, Betina McNeil, Marius Bill, Malith Karunasiri, Matthew H Burke, Hatice Gulcin Ozer, Selen A Yilmaz, Nina Zitzer, Gregory K Behbehani, Christopher C Oakes, Damian J Steiner, Guido Marcucci, Bayard L Powell, Jonathan E Kolitz, Thomas H Carter, Eunice S Wang, Krzysztof Mrózek, Carlo M Croce, Michael A Caligiuri, Clara D Bloomfield, Ramiro Garzon, Adrienne M Dorrance. Proceedings of the National Academy of Sciences of the United States of America. 2017 June;114:E4641-E4647. [Full Text Article]
[PubMed:28533390]
[PMC:PMC5468639]
Related Antibodies: LS-C153302, LS-C40134.
☰ Filters
Products
Proteins
(12)
Type
Over-Expression Lysate
(4)
Recombinant
(8)
Target
EGFL7
(12)
Publications
No
(12)
Tag
GST
(1)
GST, N-terminus + His, C-terminus
(1)
His-S
(1)
His-T7
(1)
Myc-DDK (Flag)
(5)
Species
Human
(8)
Mouse
(2)
Source
293T Cells
(2)
E. coli
(4)
HEK 293 Cells
(3)
Insect Cells
(2)
Wheat Germ Extract
(1)
Purification
Purified
(2)
Low Endotoxin Level
Low endotoxin level
(3)
Biologically Active
Biologically active
(2)
E. coli
None
Less than 0.1 ng/µg of protein (less than 1EU/µg).
28 kDa
2 µg/$268; 10 µg/$349
Insect Cells
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
25 µg/$975
HEK 293 Cells
Myc-DDK (Flag)
29.4 kDa
100 µg/$494
HEK 293 Cells
Myc-DDK (Flag)
29.4 kDa
100 µg/$494
HEK 293 Cells
Myc-DDK (Flag)
29.4 kDa
20 µg/$1,107
293T Cells
Myc-DDK (Flag)
29.4 kDa
20 µg/$150
293T Cells
Myc-DDK (Flag)
29.4 kDa
20 µg/$150
E. coli
His-T7
30.8 kDa
10 µg/$282; 50 µg/$447; 100 µg/$715; 200 µg/$892; 1 mg/$2,005; 500 µg/$1,543; 5 mg/$3,123; 2 mg/$2,192
E. coli
His-S
31.2 kDa
10 µg/$284; 50 µg/$460; 100 µg/$735; 200 µg/$917; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225
E. coli
GST, N-terminus + His, C-terminus
57.4 kDa
50 µg/$419
Wheat Germ Extract
GST
53.24 kDa
2 µg/$439
Insect Cells
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
25 µg/$975
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