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Shirley, MA 01464
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EGFL6
Egf-like-domain, Multiple 6
EGFL6 is a member of the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. The gene product contains a signal peptide, suggesting that it is secreted; an EGF repeat region consisting of 4 complete EGF-like repeats and 1 partial EGF-like repeat, 3 of which have a calcium-binding consensus sequence; an arg-gly-asp integrin association motif; and a MAM domain, which is believed to have an adhesive function. This gene is expressed early during development, and its expression has been detected in lung and meningioma tumors.
| Gene Name: | Egf-like-domain, Multiple 6 |
| Synonyms: | EGFL6, EGF-like protein 6, EGF-like-domain, multiple 6, MAM and EGF domain containing, MAEG, W80 |
| Target Sequences: | NM_015507 NP_056322.2 Q8IUX8 |
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