EED

embryonic ectoderm development

Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Also recognizes 'Lys-26' trimethylated histone H1 with the effect of inhibiting PRC2 complex methyltransferase activity on nucleosomal histone H3 'Lys-27', whereas H3 'Lys-27' recognition has the opposite effect, enabling the propagation of this repressive mark. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.

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Products

Proteins (12)

Type

Over-Expression Lysate (4)

Recombinant (8)

Target

EED (12)

Publications

No (12)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His, N-Terminal (1)

His-GST (1)

His-T7 (1)

Myc-DDK (Flag) (6)

Species

Human (10)

Source

293T Cells (2)

Baculovirus (1)

E. coli (3)

HEK 293 Cells (4)

Wheat Germ Extract (2)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (1)

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Human EED Protein (Recombinant GST) (Full Length) - LS-G31298

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

76.6 kDa

Price:

10 µg/$479; 25 µg/$670

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Human EED Protein (Recombinant His-GST) (Met1-Arg441) - LS-G97405

Source:

Baculovirus

Tag:

His-GST

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

78 kDa

Price:

100 µg/$721

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EED Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G105960

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

45.3 kDa

Price:

100 µg/$494

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Human EED Protein (Recombinant His, N-Terminal) - LS-G144339

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

50 kDa

Price:

50 µg/$419

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Human EED Protein (Recombinant His) - LS-G2373

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human EED Protein (Recombinant His-T7) (aa142-441) - LS-G24694

Source:

E. coli

Tag:

His-T7

Molecular Weight:

38.4 kDa

Price:

10 µg/$255; 50 µg/$323; 100 µg/$450; 200 µg/$562; 1 mg/$1,480; 500 µg/$1,096; 5 mg/$2,395; 2 mg/$1,646

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Human EED Protein (Recombinant GST, N-terminus) (aa342-441) - LS-G60840

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human EED Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68326

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

50 kDa

Price:

20 µg/$1,107

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Human EED Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68328

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

45.3 kDa

Price:

20 µg/$1,107

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Human EED Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81936

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

50 kDa

Price:

20 µg/$215

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Human EED Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81937

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

45.3 kDa

Price:

20 µg/$150

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EED Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100132

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

50 kDa

Price:

100 µg/$710

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