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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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EDN1 / Endothelin 1

endothelin 1

EDN1 / Endothelin 1 is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: endothelin 1
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: EDN1, Endothelin 1, Endothelin-1, ET1, Preproendothelin-1, PPET1, HDLCQ7
Target Sequences: NM_001955 NP_001946.3 P05305

Publications (1)

1
Estrogen and progesterone regulate expression of the endothelins in the rhesus macaque endometrium. Keator CS, Mah K, Ohm L, Slayden OD. Human reproduction (Oxford, England). 2011 26:1715-28. (IHC-Fr; Monkey) [Full Text Article] [PubMed:21505040] [PMC:PMC3113504] Related Antibodies: LS-C11319.

Filtered By: None
Target
EDN1 / Endothelin 1 (136)
Reactivity
Human (101)
Mouse (13)
Rat (13)
Bovine (1)
Caiman (1)
Cow (1)
Dog (1)
Goat (1)
Monkey (1)
Pig (18)
Sheep (1)
Application
IHC (84)
IHC-Fr (5)
IHC-P (10)
WB (86)
Flo (8)
ELISA (30)
ICC (23)
IF (23)
IP (2)
RIA (26)
Host
rabbit (77)
mouse (52)
rat (7)
Isotype
IgG (78)
IgG1 (32)
IgG2a,k (1)
IgG2b (7)
IgG2b,k (8)
Clonality
monoclonal mc (58)
polyclonal pc (78)
Clone
1C4 (1)
20-2101.70 (1)
20-2111.41 (1)
20-2125.4 (1)
20-2201.1 (1)
3D6 (1)
IC4 (1)
Format
AP Conjugated (8)
APC (6)
APC Conjugated (13)
Azide-free (2)
Biotin Conjugated (15)
Cy3 Conjugated (6)
Cy7 Conjugated (6)
FITC Conjugated (16)
HRP Conjugated (14)
PE Conjugated (14)
Unconjugated (44)
Epitope
aa53-203 (16)
aa33-202 (10)
aa53-90 (10)
aa111-138 (8)
aa176-203 (8)
aa54-202 (8)
C-Terminus (4)
Internal (2)
aa22-38 (2)
aa141-212 (1)
aa15-21 (1)
Publications
No (135)
Yes (1)
Showing 1-25 of 136 results

EDN1 / Endothelin 1 Antibody (aa53-90) IHC-plus™ LS-B14598
Mouse Monoclonal (IgG) to Human EDN1 / Endothelin 1
Human
ICC IHC IHC-P IP WB
Unconjugated
100µg 1mg/ml  $425.00
Human Placenta, Vessels: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot of recombinant EDN1 / Endothelin 1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Placenta, Vessels: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot of recombinant EDN1 / Endothelin 1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

EDN1 / Endothelin 1 Antibody (aa111-138) LS-C167624
Rabbit Polyclonal to Human EDN1 / Endothelin 1
Human
Flo IF IHC IHC-P WB
Unconjugated
400µl  $305.00
EDN1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human placenta tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Confocal immunofluorescence of EDN1 Antibody with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
EDN1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human placenta tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Confocal immunofluorescence of EDN1 Antibody with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

EDN1 / Endothelin 1 Antibody (C-Terminus, clone 1C4) LS-C11319
Publications (1)
Publications (1)
Mouse Monoclonal [clone 1C4] (IgG1) to Human EDN1 / Endothelin 1
Human, Monkey
IHC IHC-Fr RIA
Unconjugated
100µg 1mg/ml  $335.00

EDN1 / Endothelin 1 Antibody (aa176-203) LS-C167623
Rabbit Polyclonal to Human EDN1 / Endothelin 1
Human
IF IHC IHC-P WB
Unconjugated
400µl  $305.00
EDN1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Confocal immunofluorescence of EDN1 Antibody with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
EDN1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Confocal immunofluorescence of EDN1 Antibody with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

EDN1 / Endothelin 1 Antibody LS-C121762
Rabbit Polyclonal to Human EDN1 / Endothelin 1
Goat, Sheep, Bovine, Pig, Human
ELISA IHC IHC-P RIA WB
Unconjugated
20µl  $435.00; 100µl  $950.00

EDN1 / Endothelin 1 Antibody (aa111-138) LS-C321020
Rabbit Polyclonal (IgG) to Human EDN1 / Endothelin 1
Human
ELISA Flo IF IHC WB
Unconjugated
200µl  $530.00

EDN1 / Endothelin 1 Antibody (aa111-138, Biotin) LS-C222325
Rabbit Polyclonal (IgG) to Human EDN1 / Endothelin 1
Human
ELISA Flo ICC IF IHC WB
Biotin Conjugated
200µl  $680.00

EDN1 / Endothelin 1 Antibody (aa111-138, FITC) LS-C222327
Rabbit Polyclonal (IgG) to Human EDN1 / Endothelin 1
Human
ELISA Flo ICC IF IHC WB
FITC Conjugated
200µl  $680.00

EDN1 / Endothelin 1 Antibody (aa111-138, AP) LS-C222323
Rabbit Polyclonal (IgG) to Human EDN1 / Endothelin 1
Human
ELISA Flo ICC IF IHC WB
AP Conjugated
200µl  $680.00

EDN1 / Endothelin 1 Antibody (aa111-138, APC) LS-C222324
Rabbit Polyclonal (IgG) to Human EDN1 / Endothelin 1
Human
ELISA Flo ICC IF IHC WB
APC Conjugated
200µl  $680.00

EDN1 / Endothelin 1 Antibody (aa111-138, Azide-free, HRP) LS-C222329
Rabbit Polyclonal (IgG) to Human EDN1 / Endothelin 1
Human
ELISA Flo ICC IF IHC WB
HRP Conjugated, Azide-free
200µl  $680.00

EDN1 / Endothelin 1 Antibody (aa111-138, PE) LS-C222330
Rabbit Polyclonal (IgG) to Human EDN1 / Endothelin 1
Human
ELISA Flo ICC IF IHC WB
PE Conjugated
200µl  $680.00

EDN1 / Endothelin 1 Antibody (aa176-203) LS-C329492
Rabbit Polyclonal (IgG) to Human EDN1 / Endothelin 1
Human
ELISA IF IHC WB
Unconjugated
200µl  $530.00

EDN1 / Endothelin 1 Antibody (aa176-203, Biotin) LS-C222319
Rabbit Polyclonal (IgG) to Human EDN1 / Endothelin 1
Human
ELISA ICC IF IHC WB
Biotin Conjugated
200µl  $680.00

EDN1 / Endothelin 1 Antibody (aa176-203, FITC) LS-C222320
Rabbit Polyclonal (IgG) to Human EDN1 / Endothelin 1
Human
ELISA ICC IF IHC WB
FITC Conjugated
200µl  $680.00

EDN1 / Endothelin 1 Antibody (aa176-203, AP) LS-C222317
Rabbit Polyclonal (IgG) to Human EDN1 / Endothelin 1
Human
ELISA ICC IF IHC WB
AP Conjugated
200µl  $680.00

EDN1 / Endothelin 1 Antibody (aa176-203, APC) LS-C222318
Rabbit Polyclonal (IgG) to Human EDN1 / Endothelin 1
Human
ELISA ICC IF IHC WB
APC Conjugated
200µl  $680.00

EDN1 / Endothelin 1 Antibody (aa176-203, Azide-free, HRP) LS-C222321
Rabbit Polyclonal (IgG) to Human EDN1 / Endothelin 1
Human
ELISA ICC IF IHC WB
HRP Conjugated, Azide-free
200µl  $680.00

EDN1 / Endothelin 1 Antibody (aa176-203, PE) LS-C222322
Rabbit Polyclonal (IgG) to Human EDN1 / Endothelin 1
Human
ELISA ICC IF IHC WB
PE Conjugated
200µl  $680.00

EDN1 / Endothelin 1 Antibody (clone 20-2111.41) LS-C83320
Mouse Monoclonal [clone 20-2111.41] (IgG1) to Human EDN1 / Endothelin 1
Human
ELISA IF IHC IHC-P RIA
Unconjugated
100µg  $415.00
Immunofluorescent detection of mouse GnRH neuronal cells (Rajendren, G and Gibson, MJ 2001 J Neuroendocrinology 13: 270).
Immunofluorescent detection of mouse GnRH neuronal cells (Rajendren, G and Gibson, MJ 2001 J Neuroendocrinology 13: 270).

EDN1 / Endothelin 1 Antibody (clone 20-2101.70) LS-C83319
Mouse Monoclonal [clone 20-2101.70] (IgG1) to Human EDN1 / Endothelin 1
Human
ELISA IF IHC IHC-P RIA
Unconjugated
100µg  $415.00
Immunofluorescent detection of mouse GnRH neuronal cells (Rajendren, G and Gibson, MJ 2001 J Neuroendocrinology 13: 270).
Immunofluorescent detection of mouse GnRH neuronal cells (Rajendren, G and Gibson, MJ 2001 J Neuroendocrinology 13: 270).

EDN1 / Endothelin 1 Antibody (clone 20-2125.4) LS-C83321
Mouse Monoclonal [clone 20-2125.4] (IgG1) to Human EDN1 / Endothelin 1
Human
ELISA IF IHC IHC-P RIA
Unconjugated
100µg  $415.00
Immunofluorescent detection of mouse GnRH neuronal cells (Rajendren, G and Gibson, MJ 2001 J Neuroendocrinology 13: 270).
Immunofluorescent detection of mouse GnRH neuronal cells (Rajendren, G and Gibson, MJ 2001 J Neuroendocrinology 13: 270).

EDN1 / Endothelin 1 Antibody (clone 20-2201.1) LS-C83322
Mouse Monoclonal [clone 20-2201.1] (IgG1) to Human EDN1 / Endothelin 1
Human
ELISA IF IHC IHC-P RIA
Unconjugated
100µg  $415.00
Immunofluorescent detection of mouse GnRH neuronal cells (Rajendren, G and Gibson, MJ 2001 J Neuroendocrinology 13: 270).
Immunofluorescent detection of mouse GnRH neuronal cells (Rajendren, G and Gibson, MJ 2001 J Neuroendocrinology 13: 270).

EDN1 / Endothelin 1 Antibody IHC-plus™ LS-B13907
Rabbit Polyclonal (IgG) to Human EDN1 / Endothelin 1
Mouse, Rat, Human
IHC IHC-P WB
Unconjugated
50µl  $425.00
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot analysis of 293T cell lysate using EDN1 antibody.
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot analysis of 293T cell lysate using EDN1 antibody.

EDN1 / Endothelin 1 Antibody LS-C744099
Rabbit Polyclonal
Mouse, Dog, Rat, Pig, Cow, Human
ELISA IF IHC-P RIA
Unconjugated
50µl  $1,140.00
Showing 1-25 of 136 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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