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EDN1 / Endothelin 1
endothelin 1
EDN1 / Endothelin 1 is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | endothelin 1 |
| Family/Subfamily: | Hormone , not assigned-Hormone |
| Synonyms: | EDN1, Endothelin 1, Endothelin-1, ET1, Preproendothelin-1, PPET1, HDLCQ7 |
| Target Sequences: | NM_001955 NP_001946.3 P05305 |
Publications (2)
1
Estrogen and progesterone regulate expression of the endothelins in the rhesus macaque endometrium. Keator CS, Mah K, Ohm L, Slayden OD. Human reproduction (Oxford, England). 2011 26:1715-28. (IHC-Fr; Monkey)
[Full Text Article]
[PubMed:21505040]
[PMC:PMC3113504]
Related Antibodies: LS-C11319.
2
B-lymphocyte-intrinsic and -extrinsic defects in secretory immunoglobulin A production in the neural crest-conditional deletion of endothelin receptor B model of Hirschsprung-associated enterocolitis. Giuliana Medrano, Frederic Cailleux, Peihong Guan, Korah Kuruvilla, Amanda J Barlow-Anacker, Ankush Gosain. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2019 June;33:7615-7624. [Full Text Article]
[PubMed:30908942]
[PMC:PMC6529339]
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Proteins
(15)
Type
Over-Expression Lysate
(4)
Recombinant
(11)
Target
EDN1 / Endothelin 1
(15)
Publications
No
(15)
Tag
6His, N-terminus
(1)
GST
(2)
GST, N-terminus
(1)
His
(4)
His, N-Terminal
(2)
Myc-DDK (Flag)
(5)
Species
Human
(8)
Mouse
(2)
Pig
(1)
Rat
(2)
Source
293T Cells
(2)
E. coli
(8)
HEK 293 Cells
(3)
Wheat Germ Extract
(2)
Purification
Purified
(3)
Low Endotoxin Level
Low endotoxin level
(1)
E. coli
6His, N-terminus
19 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365; 250 µg/$518; 500 µg/$949
E. coli
His
5.8 kDa
10 µg/$268; 50 µg/$362; 100 µg/$577; 200 µg/$722; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934
HEK 293 Cells
Myc-DDK (Flag)
24.8 kDa
100 µg/$494
E. coli
GST
29.9 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Wheat Germ Extract
GST
50.8 kDa
2 µg/$439
293T Cells
Myc-DDK (Flag)
24.8 kDa
20 µg/$150
293T Cells
Myc-DDK (Flag)
24.41 kDa
20 µg/$150
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
HEK 293 Cells
Myc-DDK (Flag)
22.4 kDa
20 µg/$1,107
HEK 293 Cells
Myc-DDK (Flag)
24.41 kDa
100 µg/$494
E. coli
194 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
21.45 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
E. coli
His, N-Terminal
19kDa
10 µg/$347; 50 µg/$852; 200 µg/$1,493; 100 µg/$1,270; 1 mg/$2,803; 500 µg/$2,298; 5 mg/$5,951; 2 mg/$3,175
E. coli
His, N-Terminal
21.0 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
E. coli
His
19.1 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
E. coli
His
18.7 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
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