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EDN1 / Endothelin 1

endothelin 1

EDN1 / Endothelin 1 is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: endothelin 1
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: EDN1, Endothelin 1, Endothelin-1, ET1, Preproendothelin-1, PPET1, HDLCQ7
Target Sequences: NM_001955 NP_001946.3 P05305

Publications (2)

1
Estrogen and progesterone regulate expression of the endothelins in the rhesus macaque endometrium. Keator CS, Mah K, Ohm L, Slayden OD. Human reproduction (Oxford, England). 2011 26:1715-28. (IHC-Fr; Monkey) [Full Text Article] [PubMed:21505040] [PMC:PMC3113504] Related Antibodies: LS-C11319.
2
B-lymphocyte-intrinsic and -extrinsic defects in secretory immunoglobulin A production in the neural crest-conditional deletion of endothelin receptor B model of Hirschsprung-associated enterocolitis. Giuliana Medrano, Frederic Cailleux, Peihong Guan, Korah Kuruvilla, Amanda J Barlow-Anacker, Ankush Gosain. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2019 June;33:7615-7624. [Full Text Article] [PubMed:30908942] [PMC:PMC6529339]

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Antibodies (104)
Primary (104)
EDN1 / Endothelin 1 (104)
Human (70)
Mouse (11)
Rat (13)
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Caiman (1)
Goat (1)
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Sheep (1)
IHC (39)
IHC-Fr (4)
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WB (80)
Flo (6)
ELISA (27)
ICC (14)
IF (19)
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rabbit (72)
mouse (31)
rat (1)
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IgG (44)
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IgG2a,k (1)
IgG2b (1)
IgG2b,k (8)
monoclonal mc (31)
polyclonal pc (73)
20-2101.70 (1)
20-2111.41 (1)
20-2125.4 (1)
20-2201.1 (1)
3D6 (1)
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Unconjugated (41)
aa53-203 (16)
aa53-90 (10)
aa33-202 (8)
aa54-202 (8)
aa176-203 (7)
aa111-138 (6)
C-Terminus (2)
Internal (2)
aa22-38 (2)
aa141-212 (1)
aa15-21 (1)
No (103)
Yes (1)
EDN1 / Endothelin 1 Antibody - Human Placenta, Vessels: Formalin-Fixed, Paraffin-Embedded (FFPE)
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EDN1 / Endothelin 1 Mouse anti-Human Monoclonal (aa53-90) Antibody
Human
ICC, IHC, IHC-P, IP, WB
Unconjugated
100 µg/$460
EDN1 / Endothelin 1 Antibody - Western Blot analysis of EDN1 expression in transfected 293T cell line by EDN1 monoclonal antibody (M01), clone 3D6.Lane 1: EDN1 transfected lysate(24 KDa).Lane 2: Non-transfected lysate.
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EDN1 / Endothelin 1 Mouse anti-Human Monoclonal (3D6) Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$423
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EDN1 / Endothelin 1 Mouse anti-Human Monoclonal (C-Terminus) (IC4) Antibody
Human
IHC, IHC-Fr, IRMA
Unconjugated
0.1 mg/$385
EDN1 / Endothelin 1 Antibody - Immunofluorescent detection of mouse GnRH neuronal cells (Rajendren, G and Gibson, MJ 2001 J Neuroendocrinology 13: 270).
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EDN1 / Endothelin 1 Mouse anti-Human Monoclonal (20-2111.41) Antibody
Human
ELISA, IF, IHC, IHC-P, RIA
Unconjugated
100 µg/$548
EDN1 / Endothelin 1 Antibody - EDN1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal (aa176-203) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal Antibody
Goat, Sheep, Bovine, Pig, Human
ELISA, IHC, IHC-P, RIA, WB
Unconjugated
20 µl/$488; 100 µl/$953
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EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal (aa22-38) Antibody
Human
IF, IHC
Unconjugated
50 µl/$572
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EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal (aa111-138) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
200 µl/$734
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EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal (aa111-138) (Biotin) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
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EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal (aa111-138) (FITC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
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EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal (aa111-138) (APC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
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EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal (aa111-138) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal (aa111-138) (PE) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
EDN1 / Endothelin 1 Antibody - Western blot of recombinant EDN1 / Endothelin 1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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EDN1 / Endothelin 1 Rabbit anti-Pig Polyclonal (aa53-203) Antibody
Pig
WB
Unconjugated
100 µl/$317; 200 µl/$362; 500 µl/$513; 1 ml/$589; 2 ml/$812; 5 ml/$1,324
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EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal (aa176-203) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
200 µl/$734
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EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal (aa176-203) (Biotin) Antibody
Human
ELISA, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
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EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal (aa176-203) (FITC) Antibody
Human
ELISA, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
Select
EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal (aa176-203) (APC) Antibody
Human
ELISA, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
Select
EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal (aa176-203) (PE) Antibody
Human
ELISA, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
Select
EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal (aa176-203) (Azide-free) (HRP) Antibody
Human
ELISA, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
EDN1 / Endothelin 1 Antibody - Immunofluorescent detection of mouse GnRH neuronal cells (Rajendren, G and Gibson, MJ 2001 J Neuroendocrinology 13: 270).
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EDN1 / Endothelin 1 Mouse anti-Human Monoclonal (20-2125.4) Antibody
Human
ELISA, IF, IHC, IHC-P, RIA
Unconjugated
100 µg/$548
EDN1 / Endothelin 1 Antibody - Immunofluorescent detection of mouse GnRH neuronal cells (Rajendren, G and Gibson, MJ 2001 J Neuroendocrinology 13: 270).
Select
EDN1 / Endothelin 1 Mouse anti-Human Monoclonal (20-2201.1) Antibody
Human
ELISA, IF, IHC, IHC-P, RIA
Unconjugated
100 µg/$548
EDN1 / Endothelin 1 Antibody - Immunofluorescent detection of mouse GnRH neuronal cells (Rajendren, G and Gibson, MJ 2001 J Neuroendocrinology 13: 270).
Select
EDN1 / Endothelin 1 Mouse anti-Human Monoclonal (20-2101.70) Antibody
Human
ELISA, IF, IHC, IHC-P, RIA
Unconjugated
100 µg/$555
EDN1 / Endothelin 1 Antibody - Western blot of recombinant EDN1 / Endothelin 1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal (aa53-90) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$325; 200 µl/$375; 500 µl/$539; 1 ml/$632; 2 ml/$867; 5 ml/$1,439
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EDN1 / Endothelin 1 Rat anti-Human Monoclonal (aa15-21) Antibody
Human
ICC, IHC, IHC-Fr
Unconjugated
1 mg/$1,435
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).