Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
EDAR is a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.
|Gene Name:||ectodysplasin A receptor|
|Synonyms:||EDAR, Ectodysplasin-A receptor, ED1R, EDA-A1 receptor, EDA1R, DL, Downless, mouse, homolog of, ED3, EDA3, ECTD10A, ECTD10B, Ectodysplasin A receptor, ED5, Downless homolog, Ectodermal dysplasia receptor, EDA-A1R, HRM1|
|Target Sequences:||NM_022336 NP_071731.1 Q9UNE0|
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