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ECI2 / PECI is a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described.
Gene Name: | enoyl-CoA delta isomerase 2 |
Synonyms: | ECI2, ACBD2, DBI-related protein 1, DJ1013A10.3, DRS1, Dodecenoyl-CoA isomerase, Enoyl-CoA delta isomerase 2, PECI, D3,D2-enoyl-CoA isomerase, DRS-1, HCA88 |
Target Sequences: | NM_006117 NP_006108.2 O75521 |
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