EBP

emopamil binding protein (sterol isomerase)

EBP is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. This protein shares structural features with bacterial and eukaryontic drug transporting proteins. It has four putative transmembrane segments and contains two conserved glutamate residues which may be involved in the transport of cationic amphiphilics. Another prominent feature of this protein is its high content of aromatic amino acid residues (>23%) in its transmembrane segments. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in this gene cause Chondrodysplasia punctata 2 (CDPX2; also known as Conradi-Hunermann syndrome).

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

EBP (3)

Publications

No (3)

Tag

Myc-DDK (Flag) (3)

Species

Human (2)

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293T Cells (1)

HEK 293 Cells (2)

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Human EBP Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69167

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.2 kDa

Price:

20 µg/$1,107

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EBP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100852

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.2 kDa

Price:

100 µg/$494

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Human EBP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83976

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.2 kDa

Price:

20 µg/$150

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