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Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. Mediates 'Lys-48'-linked polyubiquitination of substrates.
Gene Name: | ubiquitination factor E4A |
Synonyms: | UBE4A, Ubiquitination factor E4A, UFD2, UBOX2, E4, KIAA0126 |
Target Sequences: | NM_004788 NP_004779.2 Q14139 |
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