E2F4

E2F transcription factor 4, p107/p130-binding

E2F4 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated genes, and its gene mutation and increased expression may be associated with human cancer.

☰ Filters

Products

Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

E2F4 (3)

Publications

No (3)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

Select

Human E2F4 Protein (Recombinant GST) (Full Length) - LS-G28276

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

70.4 kDa

Price:

10 µg/$479; 25 µg/$670

Select

Human E2F4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79220

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.8 kDa

Price:

20 µg/$150

Select

E2F4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99602

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.8 kDa

Price:

100 µg/$494

Viewing 1-3 of 3 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.