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DYX1C1 is a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen receptors and the heat shock proteins, Hsp70 and Hsp90. An homologous protein in rat has been shown to function in neuronal migration in the developing neocortex. A chromosomal translocation involving this gene is associated with a susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream cell cycle progression 1 (CCPG1) gene.
Gene Name: | dyslexia susceptibility 1 candidate 1 |
Synonyms: | DYX1C1, DYXC1, EKN1, RD, DYX1 |
Target Sequences: | Q8WXU2 Q8WXU2 |
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