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Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis.
Gene Name: | dynein, light chain, Tctex-type 3 |
Synonyms: | DYNLT3, RP3, TCTE1L, TCTEX1L, Protein 91/23, TCTE1XL |
Target Sequences: | NM_006520 NP_006511.1 P51808 |
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