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DVL3 / Dishevelled 3

dishevelled segment polarity protein 3

DVL3 is a member of multigene family that also contains DVL1 and DVL2. The vertebrate dishevelled proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. DVL3 encodes a predicted 716-amino acid polypeptide that shows 74% nucleotide similarity with human DVL1. Similarity is particularly high in the N-terminal region and there is more divergence in the C-terminal regions. Charcot-Marie-Tooth type 2B maps to chromosome 3q. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.

Gene Name: dishevelled segment polarity protein 3
Synonyms: DVL3, DSH homolog 3, Dishevelled-3, KIAA0208
Target Sequences: NM_004423 NP_004414.3 Q92997

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Proteins (3)
Recombinant (3)
DVL3 / Dishevelled 3 (3)
No (3)
GST (1)
GST, N-terminus (1)
His-GST (1)
Human (3)
E. coli (1)
Wheat Germ Extract (2)
Purified (1)
DVL3 / Dishevelled 3 Protein - 12.5% SDS-PAGE of human DVL3 stained with Coomassie Blue
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Wheat Germ Extract
GST
104.4 kDa
10 µg/$479; 25 µg/$670
DVL3 / Dishevelled 3 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
DVL3 / Dishevelled 3 Protein - Recombinant Dishevelled, Dsh Homolog 3 By SDS-PAGE
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E. coli
His-GST
50.0 kDa
10 µg/$279; 50 µg/$430; 100 µg/$687; 200 µg/$857; 1 mg/$1,956; 500 µg/$1,499; 5 mg/$2,997; 2 mg/$2,142
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).