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Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes.
Gene Name: | dishevelled segment polarity protein 2 |
Synonyms: | DVL2, DSH homolog 2, Dishevelled-2, Dishevelled 2 |
Target Sequences: | NM_004422 NP_004413.1 O14641 |
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