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DRD1 / Dopamine Receptor D1

dopamine receptor D1

DRD1, a Dopamine Receptor, mediates the effect of the neurotransmitter dopamine, an intermediate in the biosynthesis of noradrenaline and adrenaline. It is involved in the control of motor activity and cognitive memory. Downregulation of DRD1 leads to severe impairments in working memory and to locomotor hyperactivity, which are observed in diseases such as schizophrenia, Parkinson's disease, affective disorders, and attention deficit hyperactivity disorder. DRD1 enhances smooth muscle contraction and vasodilation in the heart. It also modulates sodium transport in the kidney and is involved in the pathogenesis of hypertension.

Gene Name: dopamine receptor D1
Family/Subfamily: GPCR , Dopamine
Synonyms: DRD1, D(1A) dopamine receptor, DRD1A, DADR, D1a receptor
Target Sequences: NM_000794 NP_000785.1 P21728

Publications (2)

1
Single-molecule imaging of the functional crosstalk between surface NMDA and dopamine D1 receptors. Laurent Ladepeche, Julien P Dupuis, Delphine Bouchet, Evelyne Doudnikoff, Luting Yang, Yohan Campagne, Erwan Bézard, Eric Hosy, Laurent Groc. Proceedings of the National Academy of Sciences of the United States of America. 2013 October;110:18005-10. [Full Text Article] [PubMed:24127604] [PMC:PMC3816474] Related Antibodies: LS-C86998.
2
Increased dopamine and its receptor dopamine receptor D1 promote tumor growth in human hepatocellular carcinoma. Yan Yan, Jiahao Pan, Yonghua Chen, Wei Xing, Qiang Li, Dongyin Wang, Xiaoshuang Zhou, Jingdun Xie, Changhong Miao, Yunfei Yuan, Weian Zeng, Dongtai Chen. Cancer communications (London, England). 2020 December;40:694-710. [Full Text Article] [PubMed:33017522] [PMC:PMC7743025] Related Antibodies: LS-A44.

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Products
ELISA Kits (21)
Custom (3)
Sandwich (15)
Sandwich CLIA (3)
DRD1 / Dopamine Receptor D1 (21)
Human (5)
Mouse (5)
Rat (5)
Chicken (1)
Monkey (1)
Pig (1)
Porcine (1)
Rabbit (1)
Product Group
Alzheimer's Disease (21)
12 x 8-Well Microstrips (3)
96-Well Microplate (3)
96-Well Strip Plate (15)
No (21)
Cell Lysates (2)
Plasma (11)
Serum (11)
Tissue Homogenates (6)
DRD1 / Dopamine Receptor D1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$856
DRD1 / Dopamine Receptor D1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
DRD1 / Dopamine Receptor D1 ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
DRD1 / Dopamine Receptor D1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
DRD1 / Dopamine Receptor D1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
DRD1 / Dopamine Receptor D1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
DRD1 / Dopamine Receptor D1 ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
DRD1 / Dopamine Receptor D1 ELISA Kit
Select
Custom
96-Well Strip Plate
Pig
Colorimetric - 450nm (TMB)
1 Plate/$783
DRD1 / Dopamine Receptor D1 ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
DRD1 / Dopamine Receptor D1 ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
12.5 - 800 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
DRD1 / Dopamine Receptor D1 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Mouse
78.125 - 5000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
DRD1 / Dopamine Receptor D1 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
62.5 - 4000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
DRD1 / Dopamine Receptor D1 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
DRD1 / Dopamine Receptor D1 ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
0.391 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
DRD1 / Dopamine Receptor D1 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Rat
3.125 - 200 ng/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
DRD1 / Dopamine Receptor D1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
12.5 - 800 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
DRD1 / Dopamine Receptor D1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
DRD1 / Dopamine Receptor D1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
DRD1 / Dopamine Receptor D1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$818
DRD1 / Dopamine Receptor D1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$798
DRD1 / Dopamine Receptor D1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).