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This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4.
Gene Name: | DNA-damage regulated autophagy modulator 1 |
Family/Subfamily: | Cancer |
Synonyms: | DRAM1, DRAM |
Target Sequences: | NM_018370 NP_060840.2 Q8N682 |
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