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DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function.
Gene Name: | docking protein 3 |
Synonyms: | DOK3, Docking protein 3, Dok-like protein, DOKL |
Target Sequences: | NM_024872 NP_079148.2 Q7L591 |
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