DLX5

distal-less homeobox 5

Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5'-TAATTA-3' consensus sequence for DNA-binding.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

DLX5 (5)

Publications

No (5)

Tag

GST (1)

GST, N-terminus (1)

GST, N-terminus + His, C-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human DLX5 Protein (Recombinant GST, N-terminus + His, C-terminus) - LS-G145171

Source:

E. coli

Tag:

GST, N-terminus + His, C-terminus

Molecular Weight:

59.4 kDa

Price:

50 µg/$419

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Human DLX5 Protein (Recombinant GST) (Full Length) - LS-G28218

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

57.53 kDa

Price:

10 µg/$479; 25 µg/$670

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Human DLX5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76553

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

31.4 kDa

Price:

20 µg/$150

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Human DLX5 Protein (Recombinant GST, N-terminus) (aa1-110) - LS-G58344

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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DLX5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100483

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

31.4 kDa

Price:

100 µg/$494

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