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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
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DIRAS3 / ARHI
DIRAS family, GTP-binding RAS-like 3
DIRAS3 / ARHI is a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers. It is an imprinted gene, with monoallelic expression of the paternal allele, which is associated with growth suppression. Thus, this gene appears to be a putative tumor suppressor gene whose function is abrogated in ovarian and breast cancers.
| Gene Name: | DIRAS family, GTP-binding RAS-like 3 |
| Family/Subfamily: | Ras GTPase superfamily IPR001806 , not assigned-Ras GTPase superfamily IPR001806 |
| Synonyms: | DIRAS3, ARHI, GTP-binding protein Di-Ras3, NOEY2, RHOI |
| Target Sequences: | NM_004675 NP_004666.1 O95661 |
Publications (1)
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