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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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Dipeptidylpeptidase 10 / DPP10
dipeptidyl-peptidase 10 (non-functional)
Dipeptidylpeptidase 10 / DPP10 is a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Mutations in this gene have been associated with asthma. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
| Gene Name: | dipeptidyl-peptidase 10 (non-functional) |
| Family/Subfamily: | Protease , Serine S9B |
| Synonyms: | DPP10, Dipeptidyl peptidase X, Dipeptidyl-peptidase 10, Dipeptidylpeptidase 10, DPL2, DPRP-3, DPRP3, Dipeptidyl peptidase 10, DPPY, KIAA1492, DPP X |
| Target Sequences: | NM_020868 NP_065919.2 Q8N608 |
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