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ATP-binding RNA helicase involved in translation initiation. Part of the 43S preinitiation complex that is required for efficient initiation on mammalian mRNAs with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity.
Gene Name: | DEAH (Asp-Glu-Ala-His) box polypeptide 29 |
Synonyms: | DHX29, DDX29, DEAH box protein 29, Nucleic acid helicase DDXx |
Target Sequences: | Q7Z478 Q7Z478 |
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