Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
DHRS9 is a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. This protein demonstrates oxidoreductase activity toward hydroxysteroids and is able to convert 3-alpha-tetrahydroprogesterone to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone in the cytoplasm, and may additionally function as a transcriptional repressor in the nucleus. Alternative splicing results in multiple transcript variants.
|Gene Name:||dehydrogenase/reductase (SDR family) member 9|
|Synonyms:||DHRS9, 3-alpha-HSD, 3ALPHA-HSD, RDH-E2, RDHL, RDH15, Retinol dehydrogenase homolog, RDH-TBE, RETSDR8, SDR9C4|
|Target Sequences:||AF240697 NP_005762.2 Q9BPW9|
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.