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DGUOK / Deoxyguanosine Kinase

deoxyguanosine kinase

In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.

Gene Name: deoxyguanosine kinase
Synonyms: DGUOK, Deoxyguanosine kinase, DGK, MTDPS3
Target Sequences: AA252661

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Products
Proteins (9)
Over-Expression Lysate (4)
Recombinant (5)
DGUOK / Deoxyguanosine Kinase (9)
No (9)
GST (1)
GST, N-terminus (1)
His, N-Terminal (1)
His-SUMO (1)
Myc-DDK (Flag) (5)
Human (7)
293T Cells (2)
E. coli (2)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (1)
DGUOK / Deoxyguanosine Kinase Protein
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E. coli
His-SUMO
43.9 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
DGUOK / Deoxyguanosine Kinase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
17.3 kDa
100 µg/$494
DGUOK / Deoxyguanosine Kinase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
27.9 kDa
100 µg/$494
DGUOK / Deoxyguanosine Kinase Protein
Select
E. coli
His, N-Terminal
17.3 kDa
50 µg/$419
DGUOK / Deoxyguanosine Kinase Protein - 12.5% SDS-PAGE of human DGUOK stained with Coomassie Blue
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Wheat Germ Extract
GST
56.21 kDa
2 µg/$439
DGUOK / Deoxyguanosine Kinase Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
DGUOK / Deoxyguanosine Kinase Protein - Purified recombinant protein DGUOK was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
27.9 kDa
20 µg/$1,107
DGUOK / Deoxyguanosine Kinase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
27.9 kDa
20 µg/$150
DGUOK / Deoxyguanosine Kinase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
17.3 kDa
20 µg/$150
Viewing 1-9 of 9 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).