DERL2 / Derlin-2

derlin 2

Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

DERL2 / Derlin-2 (3)

Publications

No (3)

Tag

Myc-DDK (Flag) (3)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (2)

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Human DERL2 / Derlin-2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88698

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

27.4 kDa

Price:

20 µg/$150

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Human DERL2 / Derlin-2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71079

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

27.4 kDa

Price:

20 µg/$1,107

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DERL2 / Derlin-2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101375

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

27.4 kDa

Price:

100 µg/$494

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