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DEFA6 / Defensin 6

defensin, alpha 6, Paneth cell-specific

Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 6, is highly expressed in the secretory granules of Paneth cells of the small intestine, and likely plays a role in host defense of human bowel.

Gene Name: defensin, alpha 6, Paneth cell-specific
Synonyms: DEFA6, Defensin, alpha 6, Defensin 6, Defensin-6, HD-6
Target Sequences: NM_001926 NP_001917.1 Q01524

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
DEFA6 / Defensin 6 (5)
No (5)
GST (1)
His-GST-S (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
DEFA6 / Defensin 6 Protein - Purified recombinant protein DEFA6 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
8.9 kDa
20 µg/$1,107
DEFA6 / Defensin 6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
10.98 kDa
100 µg/$494
DEFA6 / Defensin 6 Protein - Recombinant  Defensin Alpha 6, Paneth Cell Specific By SDS-PAGE
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E. coli
His-GST-S
38.9 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
DEFA6 / Defensin 6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
10.98 kDa
20 µg/$150
DEFA6 / Defensin 6 Protein - 12.5% SDS-PAGE of human DEFA6 stained with Coomassie Blue
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Wheat Germ Extract
GST
37.4 kDa
10 µg/$479; 25 µg/$670
Viewing 1-5 of 5 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).