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DEF6

differentially expressed in FDCP 6 homolog (mouse)

Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which plays a role in the activation of Rho GTPases RAC1, RhoA and CDC42. Can regulate cell morphology in cooperation with activated RAC1. Plays a role in Th2 (T helper cells) development and/or activation, perhaps by interfering with ZAP70 signaling.

Gene Name: differentially expressed in FDCP 6 homolog (mouse)
Synonyms: DEF6, DEF-6, IBP, SLAT, SWAP70L, IRF4-binding protein
Target Sequences: NM_022047 NP_071330.3 Q9H4E7

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Products
Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
DEF6 (5)
No (5)
GST (1)
His, N-Terminal (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
DEF6 Protein - 12.5% SDS-PAGE of human DEF6 stained with Coomassie Blue
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Wheat Germ Extract
GST
62.7 kDa
10 µg/$479; 25 µg/$670
DEF6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
73.7 kDa
100 µg/$710
DEF6 Protein
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E. coli
His, N-Terminal
73.7 kDa
50 µg/$419
DEF6 Protein - Purified recombinant protein DEF6 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
73.7 kDa
20 µg/$1,107
DEF6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
73.7 kDa
20 µg/$215
Viewing 1-5 of 5 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).