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DDX56
DEAD (Asp-Glu-Ala-Asp) box helicase 56
DDX56 is a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene shows ATPase activity in the presence of polynucleotides and associates with nucleoplasmic 65S preribosomal particles. This gene may be involved in ribosome synthesis, most likely during assembly of the large 60S ribosomal subunit. Multiple transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | DEAD (Asp-Glu-Ala-Asp) box helicase 56 |
| Family/Subfamily: | DEAD box protein |
| Synonyms: | DDX56, 61-kd nucleolar helicase, DEAD-box RNA helicase, DEAD box protein 56, DEAD box protein 21, Nucleolar helicase of 61 kDa, NOH61, DDX26 |
| Target Sequences: | NM_019082 NP_061955.1 Q9NY93 |
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