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DDX23 / PRP28

DEAD (Asp-Glu-Ala-Asp) box polypeptide 23

DDX23 / PRP28 is a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined.

Gene Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
Family/Subfamily: DEAD box protein
Synonyms: DDX23, DEAD box protein 23, PRP28 homolog, yeast, PRPF28, Prp28, U5-100KD, U5 snRNP 100 kD protein, PRP28 homolog, PRP28p homolog, U5-100K
Target Sequences: NM_004818 NP_004809.2 Q9BUQ8

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
DDX23 / PRP28 (3)
No (3)
Myc-DDK (Flag) (3)
Human (2)
293T Cells (1)
HEK 293 Cells (2)
DDX23 / PRP28 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
95.4 kDa
100 µg/$494
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293T Cells
Myc-DDK (Flag)
95.4 kDa
20 µg/$150
DDX23 / PRP28 Protein - Purified recombinant protein DDX23 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
95.4 kDa
20 µg/$1,107
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).